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Bio-Engineered Skin Substitutes
Tissue of human origin or bio-engineered tissue used to support wound closure and serve as a replacement for skin and surgical grafting. A bio-engineered skin substitute closely resembles human skin in structure, function and handling, and may provide both epidermal and dermal components.
Hyperbaric Medicine
The systemic delivery of oxygen to the tissues while placed in a unit which has been compressed to approximately 2-2.4 ATA. Hyperbaric medicine stimulates angiogenesis and fibroblast migration, enhances neutrophil and antibiotic killing action, and suppresses alpha toxin production in gas gangrene.
Growth Factor Therapy
Research has determined that proteins which occur naturally in the body are integral in stimulating cell growth and migration, necessary for wound healing. These growth factors (proteins) are manufactured through recombinant DNA technology, and applied to the wound as a daily topical treatment, in combination with comprehensive wound management.
Negative Pressure Therapy
A non invasive therapy that uses controlled, localized negative pressure to stimulate the growth of healthy granulation tissue. This occurs through the removal of wound fluid, which helps to manage bacterial bioburden, and well as support a moist wound environment to enhance cell migration and epithelialization.
Biologicals and Biosynthetics
Gels or solutions derived from natural sources which are applied to the wound base to stimulate wound healing.
Electrical Stimulation
The use of a capacitive coupled electrical current to transfer energy to a wound. Then flow of this electrical current in the tissue attracts key cells which are necessary to initiate the inflammatory response, fight infection, and stimulate fibroblast migration and granulation tissue formation.
Total Contact Casting
A treatment used for successful offweighting of plantar foot ulcerations. Total contact casting provides decreased plantar surface pressures over wounded areas of the foot, by redistributing weight bearing over the entire lower leg.
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